Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
glutathione Sepharose column chromatography, and gel filtration | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | high expression | Mus musculus | - |
brain cortex | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
inositol hexakisphosphate kinase-1 | - |
Mus musculus |
IP6K1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | glycogen synthase kinase 3 activity is inhibited in the brains of IP6K1-deleted mice. Enzyme deletion disrupts social behavior | Mus musculus |
physiological function | IP6K1 binds and stimulates (4fold) glycogen synthase kinase 3 alpha and beta isoforms enzymatic activity in vitro in a catalytically independent mechanism (physiological activator) | Mus musculus |