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Literature summary for 2.7.4.26 extracted from
- Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate (2006), J. Bacteriol., 188, 3192-3198.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli BL21 | Methanocaldococcus jannaschii |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.256 | - |
isopentenyl phosphate | pH 7.5, 55°C | Methanocaldococcus jannaschii |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + isopentenyl phosphate | Methanocaldococcus jannaschii | involved in the mevalonate pathway | ADP + isopentenyl diphosphate | - |
? | |
| ATP + isopentenyl phosphate | Methanocaldococcus jannaschii DSM 2661 | involved in the mevalonate pathway | ADP + isopentenyl diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanocaldococcus jannaschii | Q60352 | - |
- |
| Methanocaldococcus jannaschii DSM 2661 | Q60352 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + isopentenyl phosphate | strictly specific for ATP | Methanocaldococcus jannaschii | ADP + isopentenyl diphosphate | - |
? | |
| ATP + isopentenyl phosphate | involved in the mevalonate pathway | Methanocaldococcus jannaschii | ADP + isopentenyl diphosphate | - |
? | |
| ATP + isopentenyl phosphate | strictly specific for ATP | Methanocaldococcus jannaschii DSM 2661 | ADP + isopentenyl diphosphate | - |
? | |
| ATP + isopentenyl phosphate | involved in the mevalonate pathway | Methanocaldococcus jannaschii DSM 2661 | ADP + isopentenyl diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MJ0044 | - |
Methanocaldococcus jannaschii |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 330 | - |
isopentenyl phosphate | pH 7.5, 55°C | Methanocaldococcus jannaschii | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Methanocaldococcus jannaschii |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9 | - |
Methanocaldococcus jannaschii |
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Release 2023.1 (January 2023)
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