Protein Variants | Comment | Organism |
---|---|---|
K135L | isoform B, mutation in dimeric interface, defective DNA-binding and reduced stability of enzyme | Homo sapiens |
N69H | isoform B, mutation in dimeric interface, defective DNA-binding and reduced stability of enzyme | Homo sapiens |
R34G | isoform B, mutation in dimeric interface, defective DNA-binding and reduced stability of enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoforms A and B | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | isoforms A,B in the ratio 1:1 | Homo sapiens | - |
placenta | isoforms A,B in the ratio 1:3 | Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
hexamer | erythrocyte: different heterohexamers of isoforms A,B, main form is 3 * A + 3 * B, placenta: pure isoform B and heteromeric 1:1 mixture of isoforms A,B, SDS-PAGE | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
3 h, 50% loss of activity | Homo sapiens |