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Literature summary for 2.7.4.8 extracted from
- The mouse guanylate kinase double mutant E72Q/D103N is a functional adenylate kinase (2001), Protein Eng., 14, 903-909.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D103N | active | Mus musculus |
| E72Q | no guanylate or adenylate kinase activity | Mus musculus |
| E72Q/D103D | no active | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0012 | - |
E72Q mutant | Mus musculus |
| 0.0032 | - |
D103N mutant, adenylate kinase activity | Mus musculus |
| 0.0057 | - |
E72Q mutant, adenylate kinase activity | Mus musculus |
| 0.024 | - |
E72Q/D103N mutant | Mus musculus |
| 0.088 | - |
D103N mutant | Mus musculus |
| 0.44 | - |
- |
Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + dGMP | - |
Mus musculus | ADP + dGDP | - |
? |  |
| ATP + GMP | - |
Mus musculus | ADP + GDP | - |
? | |
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Release 2023.1 (January 2023)
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