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Literature summary for 2.7.4.8 extracted from

  • Sumita, K.; Sato, Y.; Iida, J.; Kawata, A.; Hamano, M.; Hirabayashi, S.; Ohno, K.; Peles, E.; Hata, Y.
    Synaptic scaffolding molecule (S-SCAM) membrane-associated guanylate kinase with inverted organization (MAGI)-2 is associated with cell adhesion molecules at inhibitory synapses in rat hippocampal neurons (2007), J. Neurochem., 100, 154-166.
    View publication on PubMed
Search for more literature for 2.7.4.8

Cloned(Commentary)

Cloned (Comment) Organism
expression of fluorescence-tagged S-SCAM in COS-7 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
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 Rattus norvegicus 16020
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synapse S-SCAM is associated with beta-dystroglycan and neuroligin 2 at inhibitory synapses, and functions as a linker between the dystrophin glycoprotein complex and the neurexin-neuroligin complex, complex formation analysis, overview Rattus norvegicus 45202
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus synaptic scaffolding molecule, S-SCAM, is a synaptic protein, which harbors five or six PSD-95/Discs large/ZO-1, a guanylate kinase, and two WW domains. S-SCAM is associated with beta-DG and neuroligin 2 at inhibitory synapses, and functions as a linker between the dystrophin glycoprotein complex and the neurexin-neuroligin complex, complex formation analysis, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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 Rattus norvegicus
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hippocampus
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 Rattus norvegicus
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neuron from hippocampal, from rat, primary cultured Rattus norvegicus
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neuron primary hippocampal cultured neurons Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information synaptic scaffolding molecule, S-SCAM, is a synaptic protein, which harbors five or six PSD-95/Discs large/ZO-1, a guanylate kinase, and two WW domains. S-SCAM is associated with beta-DG and neuroligin 2 at inhibitory synapses, and functions as a linker between the dystrophin glycoprotein complex and the neurexin-neuroligin complex, complex formation analysis, overview Rattus norvegicus ?
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 ?

Subunits

Subunits Comment Organism
More synaptic scaffolding molecule, S-SCAM, is a synaptic protein, which harbors five or six PSD-95/Discs large/ZO-1, a guanylate kinase, and two WW domains Rattus norvegicus

Synonyms

Synonyms Comment Organism
guanylate kinase (GK)
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 Rattus norvegicus