General Stability | Organism |
---|---|
the enzyme is very labile and can be stabilized for long periods of time by its substrate thymidine 5'-monophosphate in the presence of 2-mercaptoethanol | Gallus gallus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | 25% inhibition | Gallus gallus | |
dATP | 0.4 mM, 12% inhibition, adult liver | Gallus gallus | |
dTDP | 0.4 mM, 48% inhibition | Gallus gallus | |
dTTP | 0.4 mM, 43% inhibition | Gallus gallus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Gallus gallus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement of a Mg2+:ATP ratio greater than 1.0 and for optimal activity there is a requirement of an additional 2-3 mM Mg2+ above the concentration of ATP | Gallus gallus | |
Mn2+ | can partially replace Mg2+ requirement | Gallus gallus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
46000 | - |
gel filtration | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | embryonic and adult | Gallus gallus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.188 | - |
- |
Gallus gallus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Gallus gallus |