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Literature summary for 2.7.7.15 extracted from

  • Vance, D.E.; Pelech, S.D.; Choy, P.C.
    CTP:phosphocholine cytidylyltransferase from rat liver (1981), Methods Enzymol., 71, 576-581.
No PubMed abstract available
Search for more literature for 2.7.7.15

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 diphosphate pH 6.5, 37°C, L-form of enzyme Rattus norvegicus
0.17
-
 phosphocholine pH 6.5, 37°C, L-form of enzyme Rattus norvegicus
0.21
-
 CTP CDPcholine, pH 6.5, 37°C, L-form of enzyme Rattus norvegicus
0.64
-
 CDPcholine pH 6.5, 37°C, H-form of enzyme Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000
-
 L-form of enzyme, gel filtration, aggregates in the cytosol to form high molecular weight species (H-form) with a median value of 1200000 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + choline phosphate
-
 Rattus norvegicus diphosphate + CDPcholine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Rattus norvegicus