Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
Q243A | the mutation results in loss of calmodulin binding and leads to complete calpain resistance in vitro and in vivo | Mus musculus |
General Stability | Organism |
---|---|
calmodulin stabilizes CCTalpha from calpain proteolysis | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpain | calpain degrades CCTalpha, 0.6 pmol of calpain effectively cleaves 80% of purified CCTalpha (0.7 pmol) in the absence of calmodulin | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
1 * 80000 + 1 * 30000 | Mus musculus |
80000 | - |
1 * 80000 + 1 * 30000 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + choline phosphate | - |
Mus musculus | diphosphate + CDP-choline | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | 1 * 80000 + 1 * 30000 | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
CCTalpha | - |
Mus musculus |
CTP:phosphocholine cytidylyltransferase | - |
Mus musculus |