Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Homo sapiens | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | in presence of Mg2+ and a specificity factor required for correct cleavage at the poly(A) site of pre-mRNA | Homo sapiens | |
Mn2+ | nonspecific adenylation of RNA in presence of Mn2+ | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | 60000 | gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA | Homo sapiens | the enzymatic machinery that catalyzes formation of 3'-ends of polyadenylated mRNAs consists of two distinct factors: a poly(A) polymerase and a cleavage/specificity factor required for the correct cleavage at the poly(A) site of pre-mRNA | ? | - |
? | |
ATP + RNA | Homo sapiens | involved in the 3'-end processing of mRNA | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
HeLa cells | - |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA | primer required | Homo sapiens | diphosphate + RNA(A)n | - |
? | |
ATP + RNA | enzyme also has cleavage activity | Homo sapiens | diphosphate + RNA(A)n | - |
? | |
ATP + RNA | the enzymatic machinery that catalyzes formation of 3'-ends of polyadenylated mRNAs consists of two distinct factors: a poly(A) polymerase and a cleavage/specificity factor required for the correct cleavage at the poly(A) site of pre-mRNA | Homo sapiens | ? | - |
? | |
ATP + RNA | involved in the 3'-end processing of mRNA | Homo sapiens | ? | - |
? |