Literature summary for 2.7.7.4 extracted from

Dos Santos, E.; Gritta, D.; De Almeida, J.
Analysis of interactions between potent inhibitors of ATP sulfurylase via molecular dynamics (2016), Mol. Simul., 42, 605-610 .

No PubMed abstract available

Search for more literature for 2.7.7.4

Crystallization (Commentary)

Crystallization (Comment)	Organism
molecular dynamics simulations for free enzyme and in presence of inhibitors	Thermus thermophilus

Inhibitors

Inhibitors	Comment	Organism	Structure
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid	-	Thermus thermophilus
3,5-di-tert-butyl-4-hydroxytoluene	-	Thermus thermophilus
3-tert-butyl-4-hydroxyanisole	ligand diffuses through the gate formed by residues Glu332, Thr312 and His290 to the outside of enzyme. When the gate opens, the ligand is expelled from active site of enzyme, thereafter the ligand returns when the gate closes and binds itself in another region of active site nearby the zinc atom	Thermus thermophilus

Organism

Organism	UniProt	Comment	Textmining
Thermus thermophilus	Q5SKH7	-	-

Synonyms

Synonyms	Comment	Organism
TTHA0666	-	Thermus thermophilus

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Release 2023.1 (January 2023)