Cloned (Comment) | Organism |
---|---|
- |
Haemophilus influenzae |
Protein Variants | Comment | Organism |
---|---|---|
K368A | kinetic values similar to wild-type enzyme | Haemophilus influenzae |
R18A | reduced enzyme activity | Haemophilus influenzae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.092 | - |
CTP | pH 7.2, 25°C, K386A mutant | Haemophilus influenzae | |
0.099 | - |
CTP | pH 7.2, 25°C | Haemophilus influenzae | |
0.12 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C, K386A mutant | Haemophilus influenzae | |
0.13 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C | Haemophilus influenzae | |
0.39 | - |
CTP | pH 7.2, 25°C, R18A mutant | Haemophilus influenzae | |
1 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C, R18A mutant | Haemophilus influenzae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + D-ribitol 5-phosphate | Haemophilus influenzae | - |
diphosphate + CDPribitol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus influenzae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Haemophilus influenzae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + D-ribitol 5-phosphate | - |
Haemophilus influenzae | diphosphate + CDPribitol | - |
? | |
additional information | enzyme has also ribitol 5-phosphate dehydrogenase activity | Haemophilus influenzae | ? | - |
? | |
additional information | no activity with ATP, GTP, UTP, ADP or CDP | Haemophilus influenzae | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C, R18A mutant | Haemophilus influenzae | |
9.7 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C, K386A mutant | Haemophilus influenzae | |
13 | - |
D-ribitol 5-phosphate | pH 7.2, 25°C, wild-type enzyme | Haemophilus influenzae |