Literature summary for 2.7.7.41 extracted from

Lykidis, A.; Jackson, P.; Rock, C.O.; Jackowski, S.
The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content (1997), J. Biol. Chem., 272, 33402-33409.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in COS cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
CTP + phosphatidate	Homo sapiens	the level of CDP-diacylglycerol synthetase 1 is not a critical determinant of cellular phosphatidylinositol content. This argues against a determining role of the activity in the regulation of phosphatidylinositol biosynthesis	diphosphate + CDPdiacylglycerol	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q92903	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CTP + phosphatidate	-	Homo sapiens	diphosphate + CDPdiacylglycerol	-	?
CTP + phosphatidate	the level of CDP-diacylglycerol synthetase 1 is not a critical determinant of cellular phosphatidylinositol content. This argues against a determining role of the activity in the regulation of phosphatidylinositol biosynthesis	Homo sapiens	diphosphate + CDPdiacylglycerol	-	?

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Release 2023.1 (January 2023)