Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N2-benzylguanine | the enzyme is strongly blocked, ethyl or larger groups cause preferential misincorporation and strong blockage of replicative polymerase activity | Human immunodeficiency virus 1 | |
N2-ethylguanine | the enzyme is strongly blocked, ethyl or larger groups cause preferential misincorporation and strong blockage of replicative polymerase activity | Human immunodeficiency virus 1 | |
N2-isobutylguanine | the enzyme is strongly blocked, ethyl or larger groups cause preferential misincorporation and strong blockage of replicative polymerase activity | Human immunodeficiency virus 1 | |
N2-methyl(9-anthracenyl)guanine | the enzyme is strongly blocked, ethyl or larger groups cause preferential misincorporation and strong blockage of replicative polymerase activity | Human immunodeficiency virus 1 |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00002 | - |
dCTP | - |
Human immunodeficiency virus 1 | |
0.25 | - |
dTTP | - |
Human immunodeficiency virus 1 | |
0.85 | - |
dATP | - |
Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dCTP + DNAn | - |
Human immunodeficiency virus 1 | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Human immunodeficiency virus 1 | diphosphate + DNAn+1 | - |
? | |
dTTP + poly(rA)/(dT)18 | - |
Human immunodeficiency virus 1 | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Human immunodeficiency virus 1 |