Protein Variants | Comment | Organism |
---|---|---|
additional information | expression of recombinant Candida albicans RNA 5'-triphosphatase GST-fusion protein in yeast RNA 5'-triphosphatase-deficient mutant cells binds to the guanylyltransferase of Saccharomyces cerevisiae and complements the growth defect of the mutant, while the human enzyme does not | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + pp(5')RNA | Saccharomyces cerevisiae | interaction of RNA 5'-triphosphatase and mRNA guanylyltransferase of the capping enzyme complex is essential for function and viability in vivo | G(5')ppp(5')RNA + diphosphate | guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue | r | |
GTP + pp(5')RNA | Saccharomyces cerevisiae | yeast RNA 5'-triphosphatase enzyme can be substituted by the enzyme of Candida albicans, but not by the human enzyme, to function in the capping enzyme complex together with the mRNA guanylyltransferase | G(5')ppp(5')RNA + diphosphate | guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue | r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
RNA 5'-triphosphatase-deficient mutant strain | - |
Saccharomyces cerevisiae | - |
gene CEG1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + pp(5')RNA | - |
Saccharomyces cerevisiae | G(5')ppp(5')RNA + diphosphate | guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue | ? | |
GTP + pp(5')RNA | interaction of RNA 5'-triphosphatase and mRNA guanylyltransferase of the capping enzyme complex is essential for function and viability in vivo | Saccharomyces cerevisiae | G(5')ppp(5')RNA + diphosphate | guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue | r | |
GTP + pp(5')RNA | yeast RNA 5'-triphosphatase enzyme can be substituted by the enzyme of Candida albicans, but not by the human enzyme, to function in the capping enzyme complex together with the mRNA guanylyltransferase | Saccharomyces cerevisiae | G(5')ppp(5')RNA + diphosphate | guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue | r |
Subunits | Comment | Organism |
---|---|---|
More | subunit structure of capping enzyme | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
GTase | - |
Saccharomyces cerevisiae |