Application | Comment | Organism |
---|---|---|
medicine | a single C2H2-type zinc finger domain of Zcchc11 is responsible for the functional interaction with pluripotency factor Lin28. Lin28 uses terminal uridylyltransferases Zcchc11 and Zcchc6 to control let-7 expression and has important implications for stem cell biology as well as cancer | Homo sapiens |
medicine | pluripotency factor Lin28 uses terminal uridylyltransferases Zcchc11 and Zcchc6 to control let-7 expression and has important implications for stem cell biology as well as cancer | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q5TAX3 | isoform Zcchc11, TUT4 | - |
Homo sapiens | Q5VYS8 | isoform Zcchc6, TUT7 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
More | a single C2H2-type zinc finger domain of Zcchc11 is responsible for the functional interaction with pluripotency factor Lin28. Lin28 uses terminal uridylyltransferases Zcchc11 and Zcchc6 to control let-7 expression and has important implications for stem cell biology as well as cancer | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
TUT4 | - |
Homo sapiens |
TUT7 | - |
Homo sapiens |
TUTase | - |
Homo sapiens |
Zcchc11 | - |
Homo sapiens |
ZCCHC6 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | isoforms Zcchc11 and Zcchc6 redundantly control let-7 biogenesis in embryonic stem cells | Homo sapiens |