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Literature summary for 2.7.7.6 extracted from

  • Meyer, P.A.; Ye, P.; Suh, M.H.; Zhang, M.; Fu, J.
    Structure of the 12-subunit RNA polymerase II refined with the aid of anomalous diffraction data (2009), J. Biol. Chem., 284, 12933-12939.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.6

Crystallization (Commentary)

Crystallization (Comment) Organism
purified Pol II, X-ray diffraction structuredetermination and analysis at 3.8 A resolution, single anomalous diffraction from zinc ions bound intrinsically in Pol II Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae peptide regions that interact with regulatory factors are close to the Pol II surface and assume seemingly flexible loop structures, one is located in the TFIIF-interacting protrusion domain, the other is located in the TFIIE-interacting clamp domain, conformations, overview ?
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P04050
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Purification (Commentary)

Purification (Comment) Organism
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 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information peptide regions that interact with regulatory factors are close to the Pol II surface and assume seemingly flexible loop structures, one is located in the TFIIF-interacting protrusion domain, the other is located in the TFIIE-interacting clamp domain, conformations, overview Saccharomyces cerevisiae ?
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 ?

Subunits

Subunits Comment Organism
More peptide regions that interact with regulatory factors are close to the Pol II surface and assume seemingly flexible loop structures, one is located in the TFIIF-interacting protrusion domain, the other is located in the TFIIE-interacting clamp domain, conformations, e.g. of the TFIIF-interacting Rpb2 protrusion, overview. Conformational movement and dynamics of fork loop-1 and -2. mechanism, overview Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
Pol II
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 Saccharomyces cerevisiae
RNA polymerase II
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 Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function RNA polymerase II is the central enzyme of eukaryotic gene expression machinery, analysis of regulation mechanisms of transcription via protein-protein interactions within the Pol II apparatus, overview Saccharomyces cerevisiae