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Literature summary for 2.7.7.7 extracted from
- The functional roles of mammalian DNA polymerase (1979), Arch. Biochem. Biophys., 198, 386-396.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aphidicolin | - |
Homo sapiens |  |
| aphidicolin | - |
Mammalia | |
| Dideoxythymidine triphosphate | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | Mammalia | overview: functional role of mammalian DNA polymerases | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | Homo sapiens | overview: functional role of mammalian DNA polymerases | diphosphate + DNAn+1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mammalia | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Mammalia | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | - |
Homo sapiens | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | overview: functional role of mammalian DNA polymerases | Mammalia | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | overview: functional role of mammalian DNA polymerases | Homo sapiens | diphosphate + DNAn+1 | - |
? | |
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