Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Benzyloxycarbonyl-Leu-Leu-al | - |
Escherichia coli | |
Benzyloxycarbonyl-Leu-Leu-al | - |
Rattus norvegicus | |
Dansyl-Leu-Leu-Leu-CH2Cl | inhibition of pol I | Escherichia coli | |
Dansyl-Leu-Leu-Leu-CH2Cl | inhibition of polymerase alpha, beta and gamma | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | Escherichia coli | - |
diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | Rattus norvegicus | - |
diphosphate + DNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Escherichia coli | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Rattus norvegicus | diphosphate + DNAn+1 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0625 | - |
Dansyl-Leu-Leu-Leu-CH2Cl | pH 8.3, 37°C | Rattus norvegicus | |
0.0656 | - |
Benzyloxycarbonyl-Leu-Leu-al | pH 8.3, 37°C | Rattus norvegicus |