Literature summary for 2.7.7.7 extracted from

Kurzynska-Kokorniak, A.; Jamburuthugoda, V.K.; Bibillo, A.; Eickbush, T.H.
DNA-directed DNA polymerase and strand displacement activity of the reverse transcriptase encoded by the R2 retrotransposon (2007), J. Mol. Biol., 374, 322-333.

Search for more literature for 2.7.7.7

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain JM109	Bombyx mori

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Bombyx mori	the R2 polymerase can utilize both RNA and DNA templates, but the processivity of the enzyme on single stranded DNA templates is higher than its processivity on RNA templates, R2-RT is also capable of synthesizing the second DNA strand during retrotransposition	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Bombyx mori	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Bombyx mori

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	-	Bombyx mori	diphosphate + DNAn+1	-	?
additional information	the R2 polymerase can utilize both RNA and DNA templates, but the processivity of the enzyme on single stranded DNA templates is higher than its processivity on RNA templates, R2-RT is also capable of synthesizing the second DNA strand during retrotransposition	Bombyx mori	?	-	?

Synonyms

Synonyms	Comment	Organism
R2 polymerase	-	Bombyx mori
R2 reverse transcriptase	capable of efficiently utilizing single-stranded DNA as a template	Bombyx mori
R2-RT	-	Bombyx mori

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Release 2023.1 (January 2023)