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Literature summary for 2.7.7.7 extracted from

  • Makarova, A.V.; Tarantul, V.Z.; Gening, L.V.
    Evolution of DNA polymerase iota structure and function in eukaryotes (2008), Biochemistry, 73, 346-352.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Gallus gallus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Mus musculus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Rattus norvegicus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Oryctolagus cuniculus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Canis lupus familiaris
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Rana temporaria
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Coturnix coturnix
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Misgurnus fossilis
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Triturus cristatus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Testudines agrionemys
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Philothamnus punctatus
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-
Coturnix coturnix
-
Quail
-
Gallus gallus
-
-
-
Misgurnus fossilis
-
river loach
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Philothamnus punctatus
-
green shrub snake
-
Rana temporaria
-
common frog
-
Rattus norvegicus
-
-
-
Testudines agrionemys
-
Horsfield’s terrapin
-
Triturus cristatus
-
crested newt
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Gallus gallus
-
brain
-
Mus musculus
-
brain
-
Rattus norvegicus
-
brain
-
Oryctolagus cuniculus
-
brain
-
Canis lupus familiaris
-
brain
-
Rana temporaria
-
brain
-
Coturnix coturnix
-
brain
-
Misgurnus fossilis
-
brain
-
Triturus cristatus
-
brain
-
Testudines agrionemys
-
brain
-
Philothamnus punctatus
-
heart
-
Gallus gallus
-
heart
-
Mus musculus
-
heart
-
Rattus norvegicus
-
heart
-
Oryctolagus cuniculus
-
heart
-
Canis lupus familiaris
-
heart
-
Rana temporaria
-
heart
-
Coturnix coturnix
-
heart
-
Misgurnus fossilis
-
heart
-
Triturus cristatus
-
heart
-
Testudines agrionemys
-
heart
-
Philothamnus punctatus
-
kidney
-
Gallus gallus
-
kidney
-
Mus musculus
-
kidney
-
Rattus norvegicus
-
kidney
-
Oryctolagus cuniculus
-
kidney
-
Canis lupus familiaris
-
kidney
-
Rana temporaria
-
kidney
-
Coturnix coturnix
-
kidney
-
Misgurnus fossilis
-
kidney
-
Triturus cristatus
-
kidney
-
Testudines agrionemys
-
kidney
-
Philothamnus punctatus
-
liver
-
Gallus gallus
-
liver
-
Mus musculus
-
liver
-
Rattus norvegicus
-
liver
-
Oryctolagus cuniculus
-
liver
-
Canis lupus familiaris
-
liver
-
Rana temporaria
-
liver
-
Coturnix coturnix
-
liver
-
Misgurnus fossilis
-
liver
-
Triturus cristatus
-
liver
-
Testudines agrionemys
-
liver
-
Philothamnus punctatus
-
lung
-
Gallus gallus
-
lung
-
Mus musculus
-
lung
-
Rattus norvegicus
-
lung
-
Oryctolagus cuniculus
-
lung
-
Canis lupus familiaris
-
lung
-
Rana temporaria
-
lung
-
Coturnix coturnix
-
lung
-
Misgurnus fossilis
-
lung
-
Triturus cristatus
-
lung
-
Testudines agrionemys
-
lung
-
Philothamnus punctatus
-
ovary
-
Gallus gallus
-
ovary
-
Mus musculus
-
ovary
-
Rattus norvegicus
-
ovary
-
Oryctolagus cuniculus
-
ovary
-
Canis lupus familiaris
-
ovary
-
Rana temporaria
-
ovary
-
Coturnix coturnix
-
ovary
-
Misgurnus fossilis
-
ovary
-
Triturus cristatus
-
ovary
-
Testudines agrionemys
-
ovary
-
Philothamnus punctatus
-
testis
-
Gallus gallus
-
testis
-
Mus musculus
-
testis
-
Rattus norvegicus
-
testis
-
Oryctolagus cuniculus
-
testis
-
Canis lupus familiaris
-
testis
-
Rana temporaria
-
testis
-
Coturnix coturnix
-
testis
-
Misgurnus fossilis
-
testis
-
Triturus cristatus
-
testis
-
Testudines agrionemys
-
testis
-
Philothamnus punctatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Gallus gallus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Mus musculus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Rattus norvegicus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Oryctolagus cuniculus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Canis lupus familiaris diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Rana temporaria diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Coturnix coturnix diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Misgurnus fossilis diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Triturus cristatus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Testudines agrionemys diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Philothamnus punctatus diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
DNA polymerase iota
-
Gallus gallus
DNA polymerase iota
-
Mus musculus
DNA polymerase iota
-
Rattus norvegicus
DNA polymerase iota
-
Oryctolagus cuniculus
DNA polymerase iota
-
Canis lupus familiaris
DNA polymerase iota
-
Rana temporaria
DNA polymerase iota
-
Coturnix coturnix
DNA polymerase iota
-
Misgurnus fossilis
DNA polymerase iota
-
Triturus cristatus
DNA polymerase iota
-
Testudines agrionemys
DNA polymerase iota
-
Philothamnus punctatus
pol iota
-
Gallus gallus
pol iota
-
Mus musculus
pol iota
-
Rattus norvegicus
pol iota
-
Oryctolagus cuniculus
pol iota
-
Canis lupus familiaris
pol iota
-
Rana temporaria
pol iota
-
Coturnix coturnix
pol iota
-
Misgurnus fossilis
pol iota
-
Triturus cristatus
pol iota
-
Testudines agrionemys
pol iota
-
Philothamnus punctatus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
Gallus gallus
37
-
-
Mus musculus
37
-
-
Rattus norvegicus
37
-
-
Oryctolagus cuniculus
37
-
-
Canis lupus familiaris
37
-
-
Rana temporaria
37
-
-
Misgurnus fossilis
37
-
-
Triturus cristatus
37
-
-
Testudines agrionemys
37
-
-
Philothamnus punctatus
42
-
-
Coturnix coturnix