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Literature summary for 2.7.7.8 extracted from

  • Bermudez-Cruz, R.M.; Garcia-Mena, J.; Montanez, C.
    Polynucleotide phosphorylase binds to ssRNA with same affinity as to ssDNA (2002), Biochimie, 84, 321-328.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNAn + a nucleoside diphosphate Escherichia coli PNPase accounts for 10% of total mRNA decay, PNPase can bind double stranded DNA, however the affinity is lower than that obtained for both RNA and single stranded DNA binding RNAn+1 + phosphate
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RNAn + a nucleoside diphosphate PNPase accounts for 10% of total mRNA decay, PNPase can bind double stranded DNA, however the affinity is lower than that obtained for both RNA and single stranded DNA binding Escherichia coli RNAn+1 + phosphate
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