Cloned (Comment) | Organism |
---|---|
expression in HeLa cell | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of polynucleotide phosphorylase in HeLa cells under oxidative stress conditions reduces RNA oxidation and increases cell viability against H2O2 insult. Knock-down of enzyme decreases viability and increases 8-oxoguanosine levels in cells exposed to H2O2 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | polynucleotide phosphorylase is involved in protecting cells and limiting damaged RNA under oxidative conditions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | polynucleotide phosphorylase is involved in protecting cells and limiting damaged RNA under oxidative conditions | Homo sapiens | ? | - |
? |