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Literature summary for 2.7.7.B5 extracted from

  • Martinez-Gomez, N.C.; Palmer, L.D.; Vivas, E.; Roach, P.L.; Downs, D.M.
    The rhodanese domain of ThiI is both necessary and sufficient for synthesis of the thiazole moiety of thiamine in Salmonella enterica (2011), J. Bacteriol., 193, 4582-4587.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Salmonella enterica

Protein Variants

Protein Variants Comment Organism
C207S using a complementation assay it is shown that mutant is required for 4-thiouridine synthesis but not for thiazole synthesis Salmonella enterica
C344S using a complementation assay it is shown that mutant is required for 4-thiouridine synthesis but not for thiazole synthesis Salmonella enterica
C456S using a complementation assay it is shown that mutant is required for 4-thiouridine synthesis and for thiazole synthesis Salmonella enterica
D189A using a complementation assay it is shown that mutant is required for 4-thiouridine synthesis but not for thiazole synthesis Salmonella enterica
K321M using a complementation assay it is shown that mutant is required for 4-thiouridine synthesis but not for thiazole synthesis Salmonella enterica

Organism

Organism UniProt Comment Textmining
Salmonella enterica
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Synonyms

Synonyms Comment Organism
ThiI bifunctional enzyme required for 4-thiouridine biosynthesis and thiamine synthesis. Adenylation activity for ThiI not required for thiazole synthesis Salmonella enterica