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Gene ontology
Version 2014-12-22
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Details for citrate (Si)-synthase activity
2.3.3.1
Gene ontology ID
GO:0004108
Definition
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group
Comment
Note that this function was formerly EC:4.1.3.7.
Synonyms
1. (R)-citric synthase activity
2. acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]
3. citrate condensing enzyme activity
4. citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity
5. citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)
6. citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]
7. citrate oxaloacetate-lyase, CoA-acetylating activity
8. citrate synthase activity
9. citrate synthetase activity
10. citric synthase activity
11. citric-condensing enzyme activity
12. citrogenase activity
13. condensing enzyme activity
14. oxalacetic transacetase activity
15. oxaloacetate transacetase activity
References
1. EC 2.3.3.1
2. ISBN 0121227073
3. MetaCyc CITSYN-RXN
4. Reactome: R-HSA-70975 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA"
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derives from the parent element
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