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Gene ontology
Version 2014-12-22
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Details for steroid 11-beta-monooxygenase activity
1.14.15.4
Gene ontology ID
GO:0004507
Definition
Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O
Synonyms
1. cytochrome P450 CYP11B1
2. cytochrome P450 CYP11B2
3. cytochrome p450 XIB1 activity
4. oxygenase, steroid 11beta -mono-
5. steroid 11-beta-hydroxylase activity
6. steroid 11-beta/18-hydroxylase activity
7. steroid 11beta-hydroxylase activity
8. steroid 11beta-monooxygenase activity
9. steroid 11beta/18-hydroxylase activity
10. steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)
References
1. EC 1.14.15.4
2. MetaCyc STEROID-11-BETA-MONOOXYGENASE-RXN
3. Reactome: R-HSA-193997 "CYP11B1 oxidises 11DCORT"
4. Reactome: R-HSA-194017 "CYP11B2 oxidises 11DCORST to CORST"
5. Reactome: R-HSA-5580292 "Defective CYP11B1 does not oxidise 11DCORT"
6. Reactome: R-HSA-5600598 "Defective CYP11B2 does not oxidise 11DCORST"
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