Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for cholesterol monooxygenase (side-chain-cleaving) activity
1.14.15.6
Gene ontology ID
GO:0008386
Definition
Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O
Synonyms
1. C27-side chain cleavage enzyme
2. cholesterol 20-22-desmolase activity
3. cholesterol C(20-22) desmolase activity
4. cholesterol C20-22 desmolase activity
5. cholesterol desmolase activity
6. cholesterol side-chain cleavage enzyme activity
7. cholesterol side-chain-cleaving enzyme activity
8. cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
9. Cyp11a1
10. cytochrome P-450(scc) activity
11. cytochrome P-450scc
12. cytochrome p450(scc) activity
13. cytochrome p450scc
14. desmolase, steroid 20-22
15. enzymes, cholesterol side-chain-cleaving
16. steroid 20-22 desmolase activity
17. steroid 20-22-lyase activity
References
1. EC 1.14.15.6
2. MetaCyc 1.14.15.6-RXN
3. Reactome: R-HSA-193054 "Oxidation of cholesterol to 22beta-hydroxycholesterol"
4. Reactome: R-HSA-193065 "Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol"
5. Reactome: R-HSA-193101 "CYP11A1 cleaves 20a,22b-DHCHOL"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
Tree view
Gene ontology