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Gene ontology
Version 2014-12-22
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Details for galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
2.4.1.135
Gene ontology ID
GO:0015018
Definition
Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
Synonyms
1. glucuronosyltransferase I activity
2. UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity
3. UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity
4. uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity
References
1. EC 2.4.1.135
2. MetaCyc 2.4.1.135-RXN
3. Reactome: R-HSA-1889955 "B3GAT dimers transfer GlcA to tetrasaccharide linker"
4. Reactome: R-HSA-3560802 "Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker"
5. Reactome: R-HSA-9638064 "B3GAT3 dimer transfers GlcA to tetrasaccharide linker"
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