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Gene ontology
Version 2014-12-22
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Details for 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
2.4.1.65
Gene ontology ID
GO:0017060
Definition
Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R
Synonyms
1. (Le(a))-dependent (alpha-3/4)-fucosyltransferase activity
2. (Lea)-dependent (alpha-3/4)-fucosyltransferase activity
3. 3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
4. alpha(1,4)-L-fucosyltransferase activity
5. alpha-(1,3/1,4) fucosyltransferase III activity
6. alpha-(1,4)-L-fucosyltransferase activity
7. alpha-(1->4)-L-fucosyltransferase activity
8. alpha-4-L-fucosyltransferase activity
9. beta-acetylglucosaminylsaccharide fucosyltransferase activity
10. blood group Lewis alpha-4-fucosyltransferase activity
11. blood-group substance Le(a)-dependent fucosyltransferase activity
12. blood-group substance Lea-dependent fucosyltransferase
13. FucT-II activity
14. galactoside 3(4)-L-fucosyltransferase activity
15. GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity
16. GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity
17. guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity
18. guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity
19. guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity
20. Lewis alpha-(1,3/4)-fucosyltransferase activity
21. Lewis alpha-(1->3/4)-fucosyltransferase activity
22. Lewis blood group alpha-(1,3/4)-fucosyltransferase activity
23. Lewis blood group alpha-(1->3/4)-fucosyltransferase activity
24. Lewis FT activity
25. Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity
26. Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity
References
1. EC 2.4.1.65
2. MetaCyc 2.4.1.65-RXN
3. Reactome: R-HSA-5693925 "FUT3 transfers L-fucose to Gal1,3GlcNAc"
4. Reactome: R-HSA-9603986 "FUT3 transfers Fuc to Type 1 chains to form LeA"
5. RHEA: 23628
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Gene ontology