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Gene ontology
Version 2014-12-22
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Details for 7-dehydrocholesterol reductase activity
1.3.1.21
Gene ontology ID
GO:0047598
Definition
Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+
Synonyms
1. 7-DHC reductase activity
2. cholesterol:NADP+ delta7-oxidoreductase activity
3. sterol Delta(7)-reductase activity
4. sterol delta7-reductase activity
References
1. EC 1.3.1.21
2. MetaCyc RXN66-323
3. Reactome: R-HSA-196402 "Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol"
4. Reactome: R-HSA-6807055 "DHCR7 reduces 7-dehydroCHOL to CHOL"
5. RHEA: 23984
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