EC Number |
Natural Substrates |
---|
2.3.1.54 | acetyl-CoA + formate |
- |
2.3.1.54 | CoA + pyruvate |
- |
2.3.1.54 | CoA + pyruvate |
formate is an important methyl group donor for anabolic pathway through the formation of folate derivates, formate supply improves Streptococcus thermophilus growth in milk |
2.3.1.54 | CoA + pyruvate |
metabolic regulation and networking, overview |
2.3.1.54 | CoA + pyruvate |
step in the mitochondrial pathway, overview |
2.3.1.54 | CoA + pyruvate |
anaerobic growth under nitrogen, 37°C, pH 7.0, extract enzyme reactions measured at room temperature |
2.3.1.54 | more |
analysis of the cytosolic proteome involving the enzyme, proteome profile |
2.3.1.54 | more |
hydrogen is formed from pyruvate by multiple parallel pathways, one pathway involves formate as an intermediate, pyruvate-formate lyase, and formate-hydrogen lyase, comprised of HydA hydrogenase and formate dehydrogenase, and a formate-independent pathway involving pyruvate dehydrogenase, the expression of pflB paralleled the expression of hydA and hyaB |
2.3.1.54 | more |
The product of yfiD gene is similar to pyruvate formate-lyase activase and it has been reported to activate PFL by replacing the glycyl radical domain, overview, the YfiD protein contributes to the pyruvate formate-lyase flux in the Escherichia coli arcA mutant strain, but not in the wild-type strain |
2.3.1.54 | more |
pyruvate formate-lyase interacts directly with the formate channel FocA to regulate formate translocation, molecular modeling of the FocA-PflB complex, the N-terminus of FocA is important for interaction with enzyme PflB |