EC Number |
Application |
Reference |
---|
2.5.1.7 | drug development |
cell-wall synthesis is an important target for antibacterial agents, and MurA is one of the few enzymes involved in the cytoplasmic stage of peptidoglycan biosynthesis which is specifically inhibited by an existing antimicrobial agent |
705785 |
2.5.1.7 | drug development |
enzyme is an ideal target for the discovery of novel antibiotics against gram-negative pathogens as they have only one copy of murA gene in its genome |
706916 |
2.5.1.7 | drug development |
MurA will be a useful target to identify potential inhibitors of fosfomycin resistance in pharmacological studies |
701948 |
2.5.1.7 | medicine |
enzyme is a target for the antibiotic fosfomycin |
-, 637599, 637602, 637603 |
2.5.1.7 | medicine |
target for development of antibacterial agents |
-, 637606, 637609 |