EC Number   |
Expression |
Reference |
|---|
    1.14.15.6 | down |
mRNA levels for CYP11A1 are significantly lower in subordinate follicles in comparison to dominant follicles and this effect is maintained following adjustment for follicle size |
706698 |
| 1.14.15.6 | down |
P450scc expression is reduced in Leydig cells treated with synthetic hormone diethylstilbestrol and natural hormone 17beta-estradiol. Diethylstilbestrol causes histone deacetylation in the P450scc promoter region, while 17beta-estradiol does not |
712924 |
| 1.14.15.6 | up |
14 days exposure of previtellogenic ovarian oocytes to nonylphenol produces a unique and consistent concentration-specific pattern of modulation of StAR and P450scc gene expression, increasing from 0 (control) to 1 and 10 micromol, and decreasing at 50 and 100 micromol |
703100 |
| 1.14.15.6 | up |
contents of soluble protein and carbohydrates in leaves and seeds of transgenic Nicotiana tabacum plants are essentially higher than the contents of these components in leaves and seeds of control plants |
703876 |
| 1.14.15.6 | up |
CYP11A1 expression is induced by Runx2in osteoblasts |
705739 |
| 1.14.15.6 | up |
CYP11A1 is elevated in dominant follicles. CYP11A1 mRNA levels are highly correlated with the focimatrix genes COL4A1, NID1 and -2 and HSPG2. Focimatrix may potentially regulate CYP11A1 expression, and the regulation of both may be important in follicular dominance |
706698 |
| 1.14.15.6 | up |
CYP11A1 mRNA expression is dramatically induced within 2 h after introduction of Runx2 protein into Runx2-null cells. CYP11A1 gene expression is induced during osteoblastic differentiation |
705739 |
| 1.14.15.6 | up |
expression of StAR and P450scc transcripts in non-steroidogenic tissues |
703100 |
| 1.14.15.6 | up |
induction of P450scc mRNA expression by 8-Br-cAMP |
712924 |
| 1.14.15.6 | up |
relationship between cortisol production and induction of transcription of steroidogenic acute regulatory (StAR) protein and P450scc. Exposure of juveniles to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and the synthetic estrogen 17alpha-ethynylestradiol produces transcriptional modulations of StAR and P450scc expression in interrenal tissue. In juvenile salmon exposed to 17alpha-ethynylestradiol, expression of P450scc mRNA is detectable in the trunk kidney, while StAR mRNA is not quantifiable. 17alpha-ethynylestradiol produces time- and concentration-specific effects on the expression of the StAR, P450scc, P450arom isoforms and IGF-2 genes in gonadal tissues. In liver and kidney tissues exposed to the endocrine disrupting chemical 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, significant induction of both StAR and P450scc mRNA |
703100 |
