EC Number   |
Expression |
Reference |
|---|
    2.7.1.74 | down |
paclitaxel significantly decreases dCK mRNA and protein levels in H460 and H520 cells |
704900 |
| 2.7.1.74 | down |
RNA-binding protein HuR silencing reduces dCK protein expression in pancreatic cancer cells |
703020 |
| 2.7.1.74 | down |
the enzyme is downregulated under hypoxic conditions |
761020 |
| 2.7.1.74 | down |
treatment with doxorubicin, trifluorothymidine or 2'-deoxy-5-fluorouridine results in downregulation of the enzyme |
759869 |
| 2.7.1.74 | up |
glutathionylation leads to increased enzyme activity. AraC and 2',2'-difluorodeoxycytidine treatment leads to increased enzyme protein but decreased enzyme activity |
759869 |
| 2.7.1.74 | up |
RNA-binding protein HuR overexpression elevates dCK protein expression in pancreatic cancer cells |
703020 |
| 2.7.1.74 | up |
the enzyme is hypoxia-induced |
722221 |
