EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
A-549 cell |
- |
668172, 685958, 689069, 695883, 740148, 740159 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
A-549 cell |
lung adenocarcinoma cell line |
667558, 668173 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
A-549 cell |
up-regulation of cyclooxygenase-2 expression by pro-inflammatory cytokines is accompanied by down-regluation of 15-hydroxyprostaglandin dehydrogenase expression. Over-expression of cyclooxygenase-2 but not -1 also attenuates 15-hydroxyprostaglandin dehydrogenase expression. Similarly, overexpression of 15-hydroxyprostaglandin dehydrogenase inhibits interleukin 1beta-induced cyclooxygenase-2 expression and results in apoptosis. The levels of 15-hydroxyprostaglandin dehydrogenase expression in transfected cells correlate positively with those of mesenchymal markers, and negatively with those of epithelial markers |
689843 |
1.1.1.21 | aldose reductase |
A-549 cell |
lung adenocarcinoma cell line |
668222 |
1.1.1.21 | aldose reductase |
A-549 cell |
type II alveolar epithelial cell line, AR expression analysis |
667420 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
A-549 cell |
- |
704451 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
A-549 cell |
- |
692332 |
1.1.1.37 | malate dehydrogenase |
A-549 cell |
- |
762064 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
A-549 cell |
- |
741406, 761332 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
A-549 cell |
- |
740908, 741464 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
A-549 cell |
- |
740924 |
1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) |
A-549 cell |
- |
763861 |
1.11.1.6 | catalase |
A-549 cell |
- |
660661 |
1.13.11.33 | arachidonate 15-lipoxygenase |
A-549 cell |
- |
704066 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
A-549 cell |
immunostaining of CMO1 in the A549 cells, overview |
726819 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
A-549 cell |
- |
726919 |
1.14.11.51 | DNA N6-methyladenine demethylase |
A-549 cell |
- |
764114 |
1.14.11.54 | mRNA N1-methyladenine demethylase |
A-549 cell |
- |
737957 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
A-549 cell |
- |
744224 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
A-549 cell |
- |
753157 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
A-549 cell |
- |
756381, 763832 |
1.14.11.69 | [histone H3]-trimethyl-L-lysine36 demethylase |
A-549 cell |
- |
753157, 754187 |
1.14.13.225 | F-actin monooxygenase |
A-549 cell |
- |
764574 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
A-549 cell |
- |
695513 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
A-549 cell |
Pseudomonas aeruginosa stimulates expression of inducible nitric oxide synthase by A-549 cells |
660685 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
A-549 cell |
- |
727426 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
A-549 cell |
lung adenocarcinoma cells |
672316 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
A-549 cell |
- |
685023 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
A-549 cell |
- |
685023 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
A-549 cell |
- |
699592 |
1.2.1.36 | retinal dehydrogenase |
A-549 cell |
- |
762901, 763529, 763530 |
1.2.1.36 | retinal dehydrogenase |
A-549 cell |
lung cancer |
656611 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
A-549 cell |
- |
763529 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
A-549 cell |
- |
746356 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
A-549 cell |
0.7% of the activity in liver |
655483 |
1.5.1.2 | pyrroline-5-carboxylate reductase |
A-549 cell |
- |
711685 |
1.5.1.6 | formyltetrahydrofolate dehydrogenase |
A-549 cell |
- |
671840, 713003 |
1.5.1.6 | formyltetrahydrofolate dehydrogenase |
A-549 cell |
inducible expression of 10-formyltetrahydrofolate dehydrogenase |
656770 |
1.5.1.6 | formyltetrahydrofolate dehydrogenase |
A-549 cell |
significantly decreased levels of FDH and its mRNA in 15 tested tumors compared with normal tissues, strong down-regulation of FDH on both the mRNA and protein level in tumors |
392350 |
1.5.3.16 | spermine oxidase |
A-549 cell |
- |
690802, 765148 |
1.5.99.B2 | proline dehydrogenase (acceptor) |
A-549 cell |
- |
689071 |
1.6.5.10 | NADPH dehydrogenase (quinone) |
A-549 cell |
- |
696015 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
A-549 cell |
- |
692674, 694350, 711167, 713005, 744505, 745830 |
1.7.1.7 | GMP reductase |
A-549 cell |
- |
659550 |
1.8.1.9 | thioredoxin-disulfide reductase |
A-549 cell |
- |
658795, 685557, 698054, 712072 |
1.8.1.9 | thioredoxin-disulfide reductase |
A-549 cell |
human lung non-small cell carcinoma |
689708 |
1.8.1.9 | thioredoxin-disulfide reductase |
A-549 cell |
TXNRD1_v3 is induced by estradiol or testosterone treatments |
687762 |
1.8.98.2 | sulfiredoxin |
A-549 cell |
- |
659421, 698052, 698928, 698993, 700520, 725510 |
1.8.98.2 | sulfiredoxin |
A-549 cell |
derived from adenocarcinoma |
765061 |
2.1.1.1 | nicotinamide N-methyltransferase |
A-549 cell |
- |
733449, 733618 |
2.1.1.137 | arsenite methyltransferase |
A-549 cell |
- |
718748, 733451 |
2.1.1.319 | type I protein arginine methyltransferase |
A-549 cell |
- |
756861 |
2.1.1.320 | type II protein arginine methyltransferase |
A-549 cell |
- |
756193, 756291, 757657 |
2.1.1.348 | mRNA m6A methyltransferase |
A-549 cell |
- |
745757, 755988 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
A-549 cell |
- |
672911 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
A-549 cell |
- |
753306 |
2.1.1.45 | thymidylate synthase |
A-549 cell |
- |
756651, 756654 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
A-549 cell |
- |
703393 |
2.1.1.77 | protein-L-isoaspartate(D-aspartate) O-methyltransferase |
A-549 cell |
- |
756674 |
2.1.2.1 | glycine hydroxymethyltransferase |
A-549 cell |
- |
756705 |
2.1.2.2 | phosphoribosylglycinamide formyltransferase 1 |
A-549 cell |
- |
736059 |
2.1.2.3 | phosphoribosylaminoimidazolecarboxamide formyltransferase |
A-549 cell |
- |
736059, 756643 |
2.1.3.2 | aspartate carbamoyltransferase |
A-549 cell |
- |
756715 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
A-549 cell |
- |
705001 |
2.3.1.24 | sphingosine N-acyltransferase |
A-549 cell |
- |
736471 |
2.3.1.258 | N-terminal methionine Nalpha-acetyltransferase NatE |
A-549 cell |
- |
740753 |
2.3.1.286 | protein acetyllysine N-acetyltransferase |
A-549 cell |
- |
738438 |
2.3.1.299 | sphingoid base N-stearoyltransferase |
A-549 cell |
- |
752796 |
2.3.1.37 | 5-aminolevulinate synthase |
A-549 cell |
sodium butyrate treatment activates ALAS2 gene transcription |
685795 |
2.3.1.4 | glucosamine-phosphate N-acetyltransferase |
A-549 cell |
- |
757009 |
2.3.1.48 | histone acetyltransferase |
A-549 cell |
- |
675963, 703846, 736413 |
2.3.1.57 | diamine N-acetyltransferase |
A-549 cell |
- |
756851 |
2.3.1.57 | diamine N-acetyltransferase |
A-549 cell |
lung-cancer derived cells |
487265 |
2.3.1.57 | diamine N-acetyltransferase |
A-549 cell |
TNFalpha can lead to the induction of NFkappaB signaling with a concomitant increase in spermidine/spermine N1-acetyltransferase expression |
674623 |
2.3.1.85 | fatty-acid synthase system |
A-549 cell |
- |
720118, 736516, 736922 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
A-549 cell |
- |
738009, 755970 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
A-549 cell |
lung cancer cell line |
659317 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
A-549 cell |
lung cancer cell line A549. After mechanical damage, TGase 2 appears to contribute to membrane resealing |
685996 |
2.3.2.32 | cullin-RING-type E3 NEDD8 transferase |
A-549 cell |
- |
745773 |
2.3.2.34 | E2 NEDD8-conjugating enzyme |
A-549 cell |
- |
756564 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
A-549 cell |
- |
759839 |
2.3.3.8 | ATP citrate synthase |
A-549 cell |
- |
672878, 735620, 756645 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
A-549 cell |
- |
702419 |
2.4.1.122 | N-acetylgalactosaminide beta-1,3-galactosyltransferase |
A-549 cell |
- |
702419 |
2.4.1.143 | alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
A-549 cell |
- |
658123 |
2.4.1.145 | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
A-549 cell |
low activity |
658123 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
A-549 cell |
- |
658123 |
2.4.1.18 | 1,4-alpha-glucan branching enzyme |
A-549 cell |
- |
660544 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
A-549 cell |
- |
702419 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
A-549 cell |
- |
702419, 719613, 756092 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
A-549 cell |
- |
703041 |
2.4.1.80 | ceramide glucosyltransferase |
A-549 cell |
high enzyme expression level and content |
736920 |
2.4.1.90 | N-acetyllactosamine synthase |
A-549 cell |
lung carcinoma cell line |
658123 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
A-549 cell |
- |
758909 |
2.4.2.14 | amidophosphoribosyltransferase |
A-549 cell |
- |
736921 |
2.4.2.26 | protein xylosyltransferase |
A-549 cell |
XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression |
702090 |
2.4.2.4 | thymidine phosphorylase |
A-549 cell |
- |
689244 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
A-549 cell |
- |
759601 |
2.5.1.18 | glutathione transferase |
A-549 cell |
- |
687298 |
2.5.1.29 | geranylgeranyl diphosphate synthase |
A-549 cell |
- |
759541 |