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Search term: artery

Results 1 - 100 of 102 > >>
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EC Number Recommended Name Source Tissue Commentary Reference
Show all pathways known for 1.1.1.49Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.49glucose-6-phosphate dehydrogenase (NADP+) artery G6PD is more than 2fold higher in pulmonary arteries compared with coronary arteries 697523
Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.12phospholipid-hydroperoxide glutathione peroxidase artery smooth muscle cells 688464
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase artery - -, 742845
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase artery - 726042
Show all pathways known for 1.14.14.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.18heme oxygenase (biliverdin-producing) artery pulmonary 684348
Show all pathways known for 1.15.1.1Display the word mapDisplay the reaction diagram Show all sequences 1.15.1.1superoxide dismutase artery internal mammary arteries 675625
Display the word mapDisplay the reaction diagram Show all sequences 1.17.3.2xanthine oxidase artery - 684354
Show all pathways known for 1.17.4.4Display the word mapDisplay the reaction diagram Show all sequences 1.17.4.4vitamin-K-epoxide reductase (warfarin-sensitive) artery mainly in vascular endothelium 675907
Show all pathways known for 1.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.3aldehyde dehydrogenase (NAD+) artery - 697280
Show all pathways known for 1.2.1.47Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.474-trimethylammoniobutyraldehyde dehydrogenase artery - 743576
Display the word mapDisplay the reaction diagram Show all sequences 1.4.3.13protein-lysine 6-oxidase artery highly expressed in vascular lesions 684889
Show all pathways known for 1.6.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.1.2NAD(P)+ transhydrogenase (Re/Si-specific) artery - 392595
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery - 685976, 710782
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery coronary artery endothelial cells 687649
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery human pulmonary artery endothelial cell, induction of NAD(P)H oxidase by exposure to hyperoxia for 3 h. Pretreatment of cells with the actin-stabilizing agent phallacidin attenuates hyperoxia-induced cortical actin thickening and reactive oxygen species production, whereas cytochalasin D and latrunculin A enhance basal and hyperoxia-induced reactive oxygen species formation. A 3-h hyperoxic exposure enhances the tyrosine phosphorylation of cortactin and interaction between cortactin and subunit p47phox. Transfection of cells with cortactin small interfering RNA or myristoylated cortactin Src homology domain 3 blocking peptide attenuated reactive oxygen species production and the hyperoxia-induced translocation of p47phox to the cell periphery 687587
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery in the mesenteric arteries of streptozotocin-induced diabetic apoE-deficient mice the expression of nox4 and gp91phox, ie. nox2 subunits of NADPH oxidase are enhanced as are endothelial nitric oxide synthase mRNA and protein 686552
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery porcine coronary artery endothelial cell, PCAEC. Exposure of cells to hypoxia for 2 h followed by 1 h of reoxygenation significantly increases reactive oxygen species formation. Pretreatment with the NADPH oxidase inhibitors, diphenyleneiodonium and apocynin , significantly attenuates hypoxia/reoxygenation-induced reactive oxygen species formation. Exposure of PCAECs to hypoxia/reoxygenation causes a significant increase in serine-threonine kinase Akt and ERK1/2 activation. Exposure of PCAEC spheroids to hypoxia/reoxygenation significantly increases endothelial spheroid sprouting, whereas pharmacological inhibition of NADPH oxidase or genetic deletion of the NADPH oxidase subunit, p47phox (p47phox/), significantly suppresses these changes 684345
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery smoking impaires acetylcholine-induced relaxations of carotid arteries, which can be improved by the NAD(P)H oxidase inhibitor apocynin. Both smoking and in vitro cigarette smoke extract exposure significantly increase vascular superoxide anion production 684343
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) artery study on enzyme activity, function, and expression in cerebral and systemic arteries. Superoxide production from enzyme is 10- to 100fold greater in intracranial arteries, basilar and middle cerebral arteries than in aorta, carotid, renal or mesenteric arteries. Isoform Nox4 shows 10fold higher expression in the basilar arteries versus aorta, carotid and mesenteric arteries 673106
Show all pathways known for 1.6.5.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.2NAD(P)H dehydrogenase (quinone) artery pulmonary arterial endothelial cell. Increase in enzyme protein and activity upon hyperoxia, i.e. exposure to 95% O2 for 48 h 671220
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.72site-specific DNA-methyltransferase (adenine-specific) artery intercranial artery 719373
Show all pathways known for 2.2.1.2Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.2transaldolase artery wall 486027
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.149Platelet-activating factor acetyltransferase artery detected by immunohistochemistry in the media of mammary arteries 693520
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase artery - 486677
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B41protein-long-chain fatty-acyl-lysine deacylase (NAD+) artery - 756672
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.224glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase artery - 736318
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.225N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase artery - 736318
Display the reaction diagram Show all sequences 2.4.3.9lactosylceramide alpha-2,3-sialyltransferase artery in atherosclerosis, excessive GM3 is synthesized in atherosclerotic lesions by macrophages and dendritic cells directly within the arterial walls in blood arteries additionally to the GM3 synthesis in blood plasma, the fatty acid compositions of GM3 from blood plasma low density lipoprotein and from atherosclerotic lesions differ 657703
Display the reaction diagram Show all sequences 2.4.3.9lactosylceramide alpha-2,3-sialyltransferase artery level of GM3 synthase in membrane-fractions isolated from the atherosclerotic intima are higher compared to those in non-dieased arterial tissue 657703
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.137phosphatidylinositol 3-kinase artery - 708145, 708681
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.153phosphatidylinositol-4,5-bisphosphate 3-kinase artery - 708686
Show all pathways known for 2.7.1.91Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.91sphingosine kinase artery gracilis muscle resistance artery. Pressure-dependent activation and translocation of isoform Sk1 by ERK1/2 is critically dependent on its serine225 phosphorylation site 701973
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.10IkappaB kinase artery mesenteric artery 761776
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.12cGMP-dependent protein kinase artery - 662462, 702471
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.13protein kinase C artery - 671952
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.13protein kinase C artery coronary 660673
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.13protein kinase C artery pulmonary 660666
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.15beta-adrenergic-receptor kinase artery - 684355
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.17Ca2+/calmodulin-dependent protein kinase artery - 722742
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.18myosin-light-chain kinase artery - 709692
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.18myosin-light-chain kinase artery maximal stimulation-induced in situ myosin light chain kinase activity is upregulated in fetal compared to adult ovine carotid arteries 684356
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.18myosin-light-chain kinase artery small resistance mesenteric artery -, 740289
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.30receptor protein serine/threonine kinase artery - 705441
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.31[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase artery intrapulmonary smooth muscle 692195
Show all pathways known for 2.7.8.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.1ethanolaminephosphotransferase artery CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes 760955
Show all pathways known for 2.7.8.2Display the word mapDisplay the reaction diagram Show all sequences 2.7.8.2diacylglycerol cholinephosphotransferase artery CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes 760955
Show all pathways known for 2.8.2.1Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.1aryl sulfotransferase artery pulmonary, endothelial cell 677196
Show all pathways known for 2.8.2.17Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.17chondroitin 6-sulfotransferase artery - 645752
Show all pathways known for 2.8.2.33Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.33N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase artery - 674051
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.8[heparan sulfate]-glucosamine N-sulfotransferase artery - 645926
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase artery nonatherogenic mammary artery 693520
Display the reaction diagram Show all sequences 3.1.26.10ribonuclease IX artery - 646297
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery - 699755, 749533
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery coronary artery smooth muscle 666160
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery first-order mesenteric resistance artery, high expression of enzyme with predominance of 3’-exon-excluded, leucine-zipper negative MYPT 1 isoform 663585
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery iliac artery, expression of leucine-zipper positive isoform of MYPT 1 predominates in healthy animal 664610
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery intrapulmonary arterial tissue, enzyme protein increases with age and is highest in adult rat. In contrast, enzyme specific activity is significantly higher in fetal compared with adult tissue 663593
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery monolayers of pulmonary artery endothelial cells 665653
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery of tail 664611
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.53[myosin-light-chain] phosphatase artery pulmonary artery, predominantly expression of 3’-exon-out/leucine-zipper positive MYPT 1 isoform 663585
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.11phosphoinositide phospholipase C artery mesenteric, pulmonary and middle cerebral arteries 751920
Show all pathways known for 3.1.4.17Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.173',5'-cyclic-nucleotide phosphodiesterase artery PDE 1 vascular expression is increased in arteries from angiotensin II hypertensive rats -, 715153
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.3phospholipase C artery intrapulmonary arteries 731015
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.353',5'-cyclic-GMP phosphodiesterase artery in the vasculature, PDE5 is the predominant PDE isoform involved in degrading cGMP 711925
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.353',5'-cyclic-GMP phosphodiesterase artery PDE5 vascular expression is decreased in arteries from angiotensin II hypertensive rats compared to control rats -, 715153
Show all pathways known for 3.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.10soluble epoxide hydrolase artery - 707303, 707309
Show all pathways known for 3.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.10soluble epoxide hydrolase artery renal, in the smooth muscle layer of the arterial wall 660664
Show all pathways known for 3.4.11.2Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.2membrane alanyl aminopeptidase artery arterial smooth muscle 683811
Display the word mapDisplay the reaction diagram Show all sequences 3.4.14.5dipeptidyl-peptidase IV artery in artery DPIV represents 92% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity 697386
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1peptidyl-dipeptidase A artery - -, 709411, 752444
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.15carboxypeptidase A2 artery mesenteric arterial bed, enzyme is identical with its pancreatic counterpart 732609
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.23angiotensin-converting enzyme 2 artery non-diseased mammary arteries and atherosclerotic carotid arteries. Total vessel wall expression of ACE and ACE2 is similar during all stages of atherosclerosis. The observed ACE2 protein is enzymatically active and activity is lower in the stable advanced atherosclerotic lesions, compared to early and ruptured atherosclerotic lesions 693806
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.37leukocyte elastase artery pulmonary artery endothelial cells 707071
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.39chymase artery gastroepiploic 81374, 81375
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.39chymase artery gastroepiploic artery 679291
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.46complement factor D artery PDGF-D is widely expressed in most neointimas in arteries exhibiting the chronic arteriopathy of chronic allograft nephropathy and is only weakly expressed in a small proportion of sclerotic arteries. The neointimal cells expressing PDGF-D are alpha-smooth muscle actin-expressing cells, but not infiltrating macrophages or endothelial cells 698194
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.6coagulation factor Xa artery middle cerebral 651191
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.7plasmin artery vessel wall 717165
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B1hyaluronan-binding serine protease artery abundant in neointima and in arteriosclerotic carotid arteries, but not in normal arteries. Accumulation in unstable coronary atherosclerotic plaques with elevated RNA expression in patients with acute coronary syndromes 687108
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B1hyaluronan-binding serine protease artery FSAP expression in stable and especially unstable coronary atherosclerotic lesions. FSAP mainly in inflammatory regions within the shoulders of the plaque surounding or located within the lipid core that is infiltrated by macrophages. Some FSAP present within fibrotic regions in the cap of the plaque. Tight colocalization of FSAP and uPA-presenting cells in all plaques. Colocalization also with CD11b/CD68. Also present in hypocellular- and lipid rich areas of atherosclerotic plaques in internal mammary arteries, absent from normal non-atherosclerotic arteries 684801
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B26proprotein convertase 5 artery - 675490
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B artery cerebral arterial walls 701244
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B60cathepsin L2 artery - -, 753117
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.24gelatinase A artery aged arterial wall, colocalization of activated enzyme and transforming growth factor TGF-beta1. Treatment of young aortic rings with activated enzyme enhances active transforming growth factor TGF-beta-1, collagen, and fibronectin expression to the level of untreated old counterparts 667356
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B artery - 695947
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.79pappalysin-1 artery - 683504
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.79pappalysin-1 artery coronary 683969
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.86ADAM 17 endopeptidase artery atherosclerotic plaque 677450
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B9ADAM9 endopeptidase artery carotid and femoral arteries, only weak ADAM-9 expression from thyroid artery without atherosclerosis 710868
Show all pathways known for 4.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.3aconitate hydratase artery coronary artery endothelial cells 747827
Show all pathways known for 4.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.1cystathionine gamma-lyase artery - 690376, 691828, 693818
Show all pathways known for 4.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.1cystathionine gamma-lyase artery tail 707582
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery - 691656
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery coronary artery 748700
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery isozymes GC-A 692548
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery pulmonary 684348, 691656, 692204
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery pulmonary, but not aorta 691541
Display the word mapDisplay the reaction diagram Show all sequences 4.6.1.2guanylate cyclase artery pulmonary, cultured model 690369
Show all pathways known for 5.3.1.8Display the word mapDisplay the reaction diagram Show all sequences 5.3.1.8mannose-6-phosphate isomerase artery - 2624
Show all pathways known for 5.3.99.4Display the word mapDisplay the reaction diagram Show all sequences 5.3.99.4prostaglandin-I synthase artery - 748544
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