Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

EC 1.1.1.136: UDP-N-acetylglucosamine 6-dehydrogenase

This is an abbreviated version!
For detailed information about UDP-N-acetylglucosamine 6-dehydrogenase, go to the full flat file.

Reaction

Show molfile
UDP-N-acetyl-alpha-D-glucosamine
+ 2 NAD+ +
Show molfile
H2O
=
Show molfile
UDP-2-acetamido-2-deoxy-alpha-D-glucuronate
+ 2 NADH + 2 H+

Synonyms

dehydrogenase, uridine diphosphoacetylglucosamine, gnaA, O180 O antigen, TviB, UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase, UDP-GlcNAc 6-dehydrogenase, UDP-GlcNAc dehydrogenase, UDP-N-acetylglucosamine C-6 dehydrogenase, UDPacetylglucosamine dehydrogenase, UGlcNAcDH, uridine 5'-diphosphate-N-acetyl-D-glucosamine oxidoreductase, uridine diphosphoacetylglucosamine dehydrogenase, WbpA

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.1361.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase

Purification

Purification on EC 1.1.1.136 - UDP-N-acetylglucosamine 6-dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Ni2+-Sepharose fast flow column
recombinant C-terminally His6-tagged TviB from Escherichia coli strain BL21(DE3) by two steps of anion exchange chromatography, affinity chromatography, and gel filtration, inactive oligomeric forms of the enzym eis removed in gel filtration, to near homogeneity
-
recombinant protein with His-tag
-