1.1.1.136: UDP-N-acetylglucosamine 6-dehydrogenase This is an abbreviated version! For detailed information about UDP-N-acetylglucosamine 6-dehydrogenase, go to the full flat file .
Reaction
UDP-N-acetyl-alpha-D-glucosamine +
2 NAD+
+
H2O =
UDP-2-acetamido-2-deoxy-alpha-D-glucuronate +
2 NADH
+
2 H+
Synonyms dehydrogenase, uridine diphosphoacetylglucosamine, gnaA, O180 O antigen, TviB, UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase, UDP-GlcNAc 6-dehydrogenase, UDP-GlcNAc dehydrogenase, UDP-N-acetylglucosamine C-6 dehydrogenase, UDPacetylglucosamine dehydrogenase, UGlcNAcDH, uridine 5'-diphosphate-N-acetyl-D-glucosamine oxidoreductase, uridine diphosphoacetylglucosamine dehydrogenase, WbpA
ECTree
Systematic Name
Systematic Name on EC 1.1.1.136 - UDP-N-acetylglucosamine 6-dehydrogenase
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UDP-N-acetyl-alpha-D-glucosamine:NAD+ 6-oxidoreductase
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide.