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1.1.1.153: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

This is an abbreviated version, for detailed information about sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), go to the full flat file.

Reaction

L-erythro-7,8-dihydrobiopterin
+
NADP+
=
sepiapterin
+
NADPH
+
H+

Synonyms

AKR1B1, MDSPR, reductase, sepiapterin, sepiapterin reductase, SPR, SR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

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Results
in table
1
Activating Compound
82
AA Sequence
3
Application
1
CAS Registry Number
16
Cloned(Commentary)
27
Cofactor
5
Crystallization (Commentary)
451
Disease/ Diagnostics
28
Engineering
2
Expression
13
General Information
2
General Stability
43
IC50 Value
148
Inhibitors
12
Ki Value [mM]
73
KM Value [mM]
11
Localization
21
Molecular Weight [Da]
93
Natural Substrates/ Products (Substrates)
299
Organism
3
Pathway
33
PDB ID
25
pH Optimum
4
pH Range
3
pH Stability
19
Purification (Commentary)
9
Reaction
3
Reaction Type
367
Reference
141
Source Tissue
10
Specific Activity [micromol/min/mg]
8
Storage Stability
216
Substrates and Products (Substrate)
13
Subunits
23
Synonyms
1
Systematic Name
16
Temperature Optimum [°C]
2
Temperature Range [°C]
3
Temperature Stability [°C]
24
Turnover Number [1/s]
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