EC 1.1.1.162: erythrulose reductase
This is an abbreviated version!
For detailed information about erythrulose reductase, go to the full flat file.
Reaction
Synonyms
D-erythrulose reductase, D-threitol:NADP+ oxidoreductase, reductase, D-erythrulose
ECTree
1.1.1.162 erythrulose reductaseAdvanced search results
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Substrates Products on EC 1.1.1.162 - erythrulose reductase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY 
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acetoin + NADPH + H+
2,3-butanediol + NADP+
-
Substrates: only slight reversibility, low activity
Products: -
Products: -
r
D-erythrulose + NAD(P)+
?
-
Substrates: one route of formation of tetritols in mammalia
Products: -
Products: -
r
isatin + NADPH
?
-
Substrates: s-cis configuration of the neighbouring carbonyls is important for activity
Products: -
Products: -
?
Phenanthrenequinone + NADPH
?
-
Substrates: s-cis configuration of the neighbouring carbonyls is important for activity
Products: -
Products: -
?
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: several substrates listed that do not serve as substrates
Products: -
Products: -
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: highly specific for D-erythrulose
Products: -
Products: -
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: highly specific for D-erythrulose
Products: -
Products: -
ir
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: highly specific for D-erythrulose
Products: in reference 2 the enzymatic reaction product of D-erythrulose is incorrectly identified as erythritol, gas-liquid and thin-layer chromatographic data have confirmed the product to be D-threitol, not erythritol, for this reason the systematic name D-threitol:NADP+ oxidoreductase should be used instead of erythritol:NADP+ oxidoreductase which has been designated by the IUB Enzyme commission
Products: in reference 2 the enzymatic reaction product of D-erythrulose is incorrectly identified as erythritol, gas-liquid and thin-layer chromatographic data have confirmed the product to be D-threitol, not erythritol, for this reason the systematic name D-threitol:NADP+ oxidoreductase should be used instead of erythritol:NADP+ oxidoreductase which has been designated by the IUB Enzyme commission
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: reversibility could not be demonstrated
Products: -
Products: -
ir
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: the equilibrium of the reaction strongly favors the reduction of D-erythrulose, the reverse reaction is slightly detectable when carried out at pH 7.5-9.0 using NADP+, erythritol does not serve as substrate
Products: in reference 2 the enzymatic reaction product of D-erythrulose is incorrectly identified as erythritol, gas-liquid and thin-layer chromatographic data have confirmed the product to be D-threitol, not erythritol, for this reason the systematic name D-threitol:NADP+ oxidoreductase should be used instead of erythritol:NADP+ oxidoreductase which has been designated by the IUB Enzyme commission
Products: in reference 2 the enzymatic reaction product of D-erythrulose is incorrectly identified as erythritol, gas-liquid and thin-layer chromatographic data have confirmed the product to be D-threitol, not erythritol, for this reason the systematic name D-threitol:NADP+ oxidoreductase should be used instead of erythritol:NADP+ oxidoreductase which has been designated by the IUB Enzyme commission
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: several substrates listed that do not serve as substrates
Products: -
Products: -
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: highly specific for D-erythrulose
Products: -
Products: -
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: highly specific for D-erythrulose
Products: reverse reaction rate is very low
Products: reverse reaction rate is very low
r
D-erythrulose + NAD(P)H
D-threitol + NAD(P)+
-
Substrates: the equilibrium of the reaction strongly favors the reduction of D-erythrulose, the reverse reaction is slightly detectable when carried out at pH 7.5-9.0 using NADP+, erythritol does not serve as substrate
Products: reverse reaction rate is very low
Products: reverse reaction rate is very low
r
diacetyl + NAD(P)H
acetoin + NADP+
-
Substrates: utilizes mainly vicinal alpha-dicarbonyls
Products: -
Products: -
ir, ?
diacetyl + NAD(P)H
acetoin + NADP+
-
Substrates: reaction is also performed by acetoin:NAD+ oxidoreductase, EC 1.1.1.5
Products: -
Products: -
ir, ?
diacetyl + NAD(P)H
acetoin + NADP+
-
Substrates: specific for alpha-dicarbonyls
Products: -
Products: -
ir, ?
diacetyl + NAD(P)H
acetoin + NADP+
-
Substrates: detoxification of food derived dicarbonyls
Products: -
Products: -
ir
