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1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase

This is an abbreviated version!
For detailed information about hydroxycyclohexanecarboxylate dehydrogenase, go to the full flat file.

Reaction

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate
+
NAD+
=
(1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate
+
NADH
+
H+

Synonyms

(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase, dihydroxycyclohexanecarboxylate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase

Reaction

Reaction on EC 1.1.1.166 - hydroxycyclohexanecarboxylate dehydrogenase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H+
show the reaction diagram
Acts on hydroxycyclohexanecarboxylates that have an equatorial carboxyl group at C-1, an axial hydroxyl group at C-3 and an equatorial hydroxyl group or carbonyl group at C-4, including (-)-quinate and (-)-shikimate
-
-
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