1.1.1.168: 2-dehydropantolactone reductase (Re-specific)

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase (Re-specific), go to the full flat file.

Word Map on EC 1.1.1.168

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

(R)-pantoyl-lactone:NADP+ oxidoreductase (A-specific), 2-dehydropantoyl-lactone reductase, 2-dehydropantoyl-lactone reductase (A-specific), 2-ketopantoyl lactone reductase, AKR, CPR, ketopantoyl lactone reductase, NADPH-dependent aldo-keto reductase, NADPH-dependent conjugated polyketone reductase, reductase, 2-oxopantoyl lactone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.168 2-dehydropantolactone reductase (Re-specific)

Substrates Products

Substrates Products on EC 1.1.1.168 - 2-dehydropantolactone reductase (Re-specific)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methylisatin + NADPH
?
show the reaction diagram
2-dehydropantolactone + NADPH + H+
(R)-pantolactone + NADP+
show the reaction diagram
2-dehydropantoyl lactone + NADPH
(R)-pantoyl lactone + NADP+
show the reaction diagram
5-bromoisatin + NADPH
?
show the reaction diagram
-
-
-
-
?
5-methylisatin + NADPH
?
show the reaction diagram
8-bromobornanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
alloxan + NADPH
?
show the reaction diagram
-
-
-
-
?
beta-naphthoquinone + NADPH
?
show the reaction diagram
-
-
-
-
?
bornanedione + NADPH
?
show the reaction diagram
camphorquinone + NADPH
?
show the reaction diagram
dihydro-4,4-diethyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-4-methyl-4-propyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-5-(2-butyl)-4-methyl-4-ethyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-5-(2-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-5-(2-pentyl)-4-methyl-4-propyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-5-(3-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
dihydro-5-isopropyl-4,4-dimethyl-2,3-furanedione + NADPH
?
show the reaction diagram
-
-
-
-
?
ethyl 2-oxopropanoate + NADPH + H+
ethyl (2R)-2-hydroxypropanoate + NADP+
show the reaction diagram
ethyl oxo(phenyl)acetate + NADPH + H+
ethyl (2R)-hydroxy(phenyl)acetate + NADP+
show the reaction diagram
isatin + NADPH
?
show the reaction diagram
ketopantoyl lactone + NADPH
?
show the reaction diagram
ketopantoyl lactone + NADPH
D-(-)-pantoyl lactone
show the reaction diagram
-
and its derivatives
-
?
methyl 2-oxopropanoate + NADPH + H+
methyl (2R)-2-hydroxypropanoate + NADP+
show the reaction diagram
0.501% activity compared to 2-dehydropantolactone
-
-
?
methyl oxo(phenyl)acetate + NADPH + H+
methyl (2R)-hydroxy(phenyl)acetate + NADP+
show the reaction diagram
3.94% activity compared to 2-dehydropantolactone
-
-
?
naphthoquinone + NADPH
?
show the reaction diagram
ninhydrin + NADPH
?
show the reaction diagram
-
-
-
-
?
oxopantoyl lactone + NADPH
?
show the reaction diagram
-
-
-
-
?
pyridine 3-aldehyde + NADPH + H+
(pyridin-3-yl)methanol + NADP+
show the reaction diagram
0.538% activity compared to 2-dehydropantolactone
-
-
?
additional information
?
-