1.1.1.169: 2-dehydropantoate 2-reductase
This is an abbreviated version!
For detailed information about 2-dehydropantoate 2-reductase, go to the full flat file.
Word Map on EC 1.1.1.169
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1.1.1.169
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pantothenate
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nadph-dependent
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pane
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hydroxymethyltransferase
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ketopantoyl
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2'-phosphate
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fragment-based
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d-2-hydroxyacid
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parapsilosis
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kodakarensis
- 1.1.1.169
- pantothenate
-
nadph-dependent
-
pane
- hydroxymethyltransferase
-
ketopantoyl
- 2'-phosphate
-
fragment-based
- d-2-hydroxyacid
-
parapsilosis
- kodakarensis
Reaction
Synonyms
2-dehydropantoate 2-reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, 2-oxopantoate reductase, conjugated polyketone reductase, CPR, ilvC, ketopantoate reductase, ketopantoic acid reductase, KPA reductase, KPR, More, PanE, panG, Tk-KPR, TK1968, TK1968 protein
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.1.1.169 - 2-dehydropantoate 2-reductase
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REACTION DIAGRAM
alpha-ketopantoate + NADPH
D-pantoate + NADP+
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pantothenate/coenzyme A biosynthetic pathway
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r
(R)-4-dehydropantoate + NADPH + H+
(R)-pantoate + NADP+
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-
-
?
(R)-4-dehydropantoate + NADPH + H+
(R)-pantoate + NADP+
-
-
-
?
(R)-pantoate + NAD+
2-dehydropantoate + NADH + H+
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-
-
r
2-dehydropantoate + NADPH + H+
-
-
-
r
(R)-pantoate + NADP+
2-dehydropantoate + NADPH + H+
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-
-
r
(R)-pantoate + NAD+
the TK1968 protein displays reductase activity specific for 2-oxopantoate and prefers NADH as the electron donor, distinct to the bacterial/eukaryotic NADPH-dependent enzymes
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-
r
2-dehydropantoate + NADH + H+
(R)-pantoate + NAD+
the TK1968 protein displays reductase activity specific for 2-oxopantoate and prefers NADH as the electron donor, distinct to the bacterial/eukaryotic NADPH-dependent enzymes
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-
r
(R)-pantoate + NADP+
an essential step for the biosynthesis of pantothenate, i.e. vitamin B5
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-
r
2-dehydropantoate + NADPH
(R)-pantoate + NADP+
the enzyme is involved in the biosynthesis of pantothenate, i.e. vitamin B5
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-
?
(R)-pantoate + NADP+
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reaction is part of the D-pantothenate biosynthesis
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-
?
2-oxopantoate + NADPH
(R)-pantoate + NADP+
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part of the pantothenate biosynthesis
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-
?
ketopantoate + NADPH
pantoate + NADP+
pantothenate biosynthetic pathway
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?
ketopantoate + NADPH
pantoate + NADP+
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the enzyme is involved in pantothenate, i.e. vitamin B5, biosynthesis, which is a precursor for CoA
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-
r
ketopantoate + NADPH
pantoate + NADP+
the enzyme is involved in pantothenate, i.e. vitamin B5, biosynthesis, which is a precursor for CoA
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-
r
ketopantoate + NADPH
pantoate + NADP+
-
-
-
?
ketopantoate + NADPH
pantoate + NADP+
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thiamine synthesis, pantothenate and thiamine biosynthetic pathway
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?