1.1.1.17: mannitol-1-phosphate 5-dehydrogenase

This is an abbreviated version!
For detailed information about mannitol-1-phosphate 5-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.17

1.1.1.17

fructose-6-phosphate

mannitol-1-phosphatase

mannitol-specific

phosphoenolpyruvate-dependent

ectocarpus

arabitol

1-phosphatase

mannitol-producing

synthesis

agriculture

analysis

pharmacology

Reaction

Synonyms

BbMPD, BMMGA3_01075, BMMGA3_RS01080, D-mannitol-1-phosphate dehydrogenase, dehydrogenase, mannitol 1-phosphate, EsM1PDH1, EsM1PDH2, EsM1PDH3, fructose 6-phosphate reductase, HAD hydrolase, family IA, variant 3, hexose reductase, HMPREF0010_00722, long-chain mannitol-1-phosphate 5-dehydrogenase, long-chain mannitol-1-phosphate dehydrogenase, M1PDH, M1PDH1, M1PDH2, M1PDH3, mannitol 1-phosphate 5-dehydrogenase, mannitol 1-phosphate dehydrogenase, mannitol-1-phosphate dehydrogenase, More, MPD, MpdA, MPDH, MPDH1, MPDH2, MPDH3, Mtl-1-P dehydrogenase, MtlD, NAD+-dependent mannitol-1-phosphate dehydrogenase, NADH-dependent mannitol-1-phosphate 5-dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.17 mannitol-1-phosphate 5-dehydrogenase

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Results	in table
4	Activating Compound
6271	AA Sequence
6	Application
1	CAS Registry Number
25	Cloned(Commentary)
68	Cofactor
1	Crystallization (Commentary)
14	Expression
29	General Information
1	General Stability
56	Inhibitors
5	kcat/KM [mM/s]
10	Ki Value [mM]
51	KM Value [mM]
13	Localization
7	Metals/Ions
22	Molecular Weight [Da]
53	Natural Substrates/ Products (Substrates)
67	Organism
6	Pathway
2	PDB ID
27	pH Optimum
8	pH Range
4	pI Value
14	Protein Variants
18	Purification (Commentary)
3	Reaction
4	Reaction Type
62	Reference
26	Source Tissue
37	Specific Activity [micromol/min/mg]
4	Storage Stability
83	Substrates and Products (Substrate)
21	Subunits
101	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
6	Temperature Range [°C]
8	Temperature Stability [°C]
5	Turnover Number [1/s]

Application

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Application on EC 1.1.1.17 - mannitol-1-phosphate 5-dehydrogenase

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agriculture

Escherichia coli

Petunia hybrida (Hook) Vilm. cv. Mitchell is transformed with an Escherichia coli gene encoding mannitol 1-phosphate dehydrogenase. The high-mannitol containing lines are more tolerant of chilling stress than the low mannitol containing transgenic lines and wild-type. In the higher mannitol lines only 0.04% to 0.06% of the total osmotic potential generated from all solutes can be attributed to mannitol, thus its action is more like that of an osmoprotectant rather than an osmoregulator. Metabolic engineering of osmoprotectant synthesis pathways can be used to improve stress tolerance in horticultural crops

669056

analysis

2 entries

pharmacology

Aspergillus fumigatus

inhibition of AfM1PDH might be a useful target for therapy of Aspergillus fumigatus infections

722234

synthesis

2 entries