1.1.1.174: cyclohexane-1,2-diol dehydrogenase
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For detailed information about cyclohexane-1,2-diol dehydrogenase, go to the full flat file.
Reaction
ECTree
1.1.1.174 cyclohexane-1,2-diol dehydrogenaseAdvanced search results
results (
results (| Results | in table |
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| 1 | CAS Registry Number |
| 1 | Cloned(Commentary) |
| 2 | Cofactor |
| 2 | Natural Substrates/ Products (Substrates) |
| 3 | Organism |
| 2 | Pathway |
| 2 | pH Optimum |
| 5 | Protein Variants |
| 1 | Purification (Commentary) |
| 1 | Reaction |
| 3 | Reaction Type |
| 3 | Reference |
| 3 | Source Tissue |
| 2 | Specific Activity [micromol/min/mg] |
| 2 | Substrates and Products (Substrate) |
| 1 | Systematic Name |
Engineering
Engineering on EC 1.1.1.174 - cyclohexane-1,2-diol dehydrogenase
for references in articles please use BRENDA:EC1.1.1.174
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
additional information
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whole-cell-catalyzed multiple regio- and stereoselective functionalizations in cascade reactions enabled by directed evolution: in Escherichia coli, expression of the recombinant enzyme leads to four different mutant whole cells, each leading to one of the three possible stereoisomeric forms of 1,2-cyclohexanediol, namely (R,R)-5, (S,S)-5, (S,R)-5 (meso), or (R,S)-5 (also meso), in a multi-step sequence, overview. Starting from the achiral substrates cyclohexane, cyclohexanol, or cyclohexanone, cyclohexane-1,2-diols as functionalized products are shown to be accessible in three different stereoisomeric forms
