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1.1.1.176: 12alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 12alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Wordmap for 1.1.1.176

Word Map on EC 1.1.1.176 Wordmap for 1.1.1.176

Reaction

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cholate
+
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NADP+
=
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3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate
+
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NADPH
+
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H+

Synonyms

12alpha-HSDH, 12alpha-hydroxy steroid dehydrogenase, CDD59475, dehydrogenase, 12alpha-hydroxy steroid, Elen_2515, NAD+-dependent 12alpha-HSDH, NAD-dependent 12alpha-hydroxysteroid dehydrogenase, NADP+-dependent 12alpha-HSDH, NADP-12alpha-hydroxysteroid dehydrogenase, NADP-dependent 12alpha-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.1761.1.1.176 12alpha-hydroxysteroid dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.176 - 12alpha-hydroxysteroid dehydrogenase

for references in articles please use BRENDA:EC1.1.1.176

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
102000 - 108000
-
native PAGE, analytical ultracentrifugation, FPLC gel filtration
110000
-
SDS-PAGE, gel filtration
125000
-
gel filtration
225000
-
gel filtration
26000
26355
calculation from sequence
58000
-
1 * 58000 + 1* 64000, SDS-PAGE
98000 - 106000
-
native PAGE, analytical ultracentrifugation