1.1.1.197: 15-hydroxyprostaglandin dehydrogenase (NADP+)

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For detailed information about 15-hydroxyprostaglandin dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

9-ketoprostaglandin reductase, carbonyl reductase, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase, prostaglandin 9-ketoreductase, prostaglandin E 9-ketoreductase, type II 15-hydroxyprostaglandin dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)

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Results

in table

24

AA Sequence

1

CAS Registry Number

1

Cloned(Commentary)

8

Cofactor

10

Inhibitors

11

KM Value [mM]

2

Molecular Weight [Da]

1

Natural Substrates/ Products (Substrates)

15

Organism

1

Pathway

5

PDB ID

6

Purification (Commentary)

1

Reaction

3

Reaction Type

15

Reference

18

Source Tissue

8

Specific Activity [micromol/min/mg]

30

Substrates and Products (Substrate)

3

Subunits

10

Synonyms

1

Systematic Name

PDB

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PDB on EC 1.1.1.197 - 15-hydroxyprostaglandin dehydrogenase (NADP+)

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PDB

SCOP

CATH

UNIPROT

ORGANISM

2 entries

Homo sapiens

2pfg, download, 3D-view

SCOPe (2pfg)

CATH (2pfg)

P16152

Homo sapiens

4z3d, download, 3D-view

SCOPe (4z3d)

CATH (4z3d)

P16152

Homo sapiens