1.1.1.206: tropinone reductase I

This is an abbreviated version!
For detailed information about tropinone reductase I, go to the full flat file.

Reaction

Synonyms

BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, EC 1.1.1.293, More, TR-I, TR1, TRI, Tri2, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, tropinone reductase-I 2, WcTR-I, WsTR-I, WsTR-I protein

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.206 tropinone reductase I

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Results	in table
1	Activating Compound
113	AA Sequence
3	Application
1	CAS Registry Number
21	Cloned(Commentary)
37	Cofactor
1	Crystallization (Commentary)
4	Expression
29	General Information
22	Inhibitors
25	kcat/KM [mM/s]
62	KM Value [mM]
3	Metals/Ions
12	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
61	Organism
5	Pathway
22	pH Optimum
3	pH Range
1	pH Stability
4	pI Value
9	Protein Variants
14	Purification (Commentary)
1	Reaction
3	Reaction Type
59	Reference
51	Source Tissue
19	Specific Activity [micromol/min/mg]
5	Storage Stability
157	Substrates and Products (Substrate)
19	Subunits
67	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
12	Temperature Stability [°C]
24	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.1.1.206 - tropinone reductase I

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-18°C, 50% glycerol, 3 weeks

Datura stramonium

-

347967

4°C, 0.46 mg protein/ml, complete inactivation of enzyme activity over night

Datura stramonium

-

347967

4°C, 2.3 mg protein/ml, 2 days, complete inactivation of enzyme activity

Datura stramonium

-

347967

4°C, 23 mg protein/ml, 9 days, complete inactivation of enzyme activity

Datura stramonium

-

347967

4°C, NADPH, NADP+ and glycerol enhance stability

Hyoscyamus niger

-

348024