1.1.1.207: (-)-menthol dehydrogenase

This is an abbreviated version!
For detailed information about (-)-menthol dehydrogenase, go to the full flat file.

Reaction

(-)-menthol
+
NADP+
=
(-)-menthone
+
NADPH
+
H+

Synonyms

(-)-menthone:(3R)-menthol reductase, dehydrogenase, menthol, menthone:(-)-menthol reductase, MMR, monoterpenoid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.207 (-)-menthol dehydrogenase

Engineering

Engineering on EC 1.1.1.207 - (-)-menthol dehydrogenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
development of a one-pot (bio)synthesis of (1R,2S,5R)-(-)-menthol and (1S,2S,5R)-(+)-neomenthol from pulegone, using recombinant Escherichia coli extracts that contain the biosynthetic genes for an ene-reductase NtDBR from Nicotiana tabacum and two menthone dehydrogenases, MMR and MNMR from Mentha piperita, a modular engineering strategy to improve the final production level. Multigene-construct-derived enzyme mixtures production of menthone, isomenthone, menthol, and neomenthol, but no or poor production of neoisomenthol and isomenthol, overview