1.1.1.214: 2-dehydropantolactone reductase (Si-specific)
This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase (Si-specific), go to the full flat file.
Reaction
Synonyms
2-dehydropantoyl-lactone reductase (B-specific), 2-ketopantoyl lactone reductase, 2-oxopantoyl lactone reductase, conjugated polyketone reductase, conjugated polyketone reductase C2, CORT_0G03830, CPR, CPR-C1, CPR-C2, ketopantoyl lactone reductase, NADPH-dependent conjugated polyketone reductase, NADPH-dependent ketopantoyl lactone reductase, nicotinamide adenine dinucleotide phosphate-dependent ketopantoyl lactone reductase
ECTree
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Engineering
Engineering on EC 1.1.1.214 - 2-dehydropantolactone reductase (Si-specific)
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D58A
site-directed mutagenesis, the mutant shows 4.82% of wild-type activity
F299A
site-directed mutagenesis, the mutant shows 19.1% of wild-type activity
F300A
site-directed mutagenesis, the mutant shows 17.8% of wild-type activity
H125A
site-directed mutagenesis, the mutant shows 1.5% of wild-type activity
K264A
site-directed mutagenesis, the mutant shows 65.7% of wild-type activity
K28A
site-directed mutagenesis, the mutant shows 71.1% of wild-type activity
K30A
site-directed mutagenesis, the mutant shows 55.1% of wild-type activity
R267A
site-directed mutagenesis, the mutant shows 8.43% of wild-type activity
T27A
site-directed mutagenesis, the mutant shows 5.75% of wild-type activity
Y63A
site-directed mutagenesis, the mutant shows 0.17% of wild-type activity
D58A
-
site-directed mutagenesis, the mutant shows 4.82% of wild-type activity
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H125A
-
site-directed mutagenesis, the mutant shows 1.5% of wild-type activity
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K28A
-
site-directed mutagenesis, the mutant shows 71.1% of wild-type activity
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K30A
-
site-directed mutagenesis, the mutant shows 55.1% of wild-type activity
-
R267A
-
site-directed mutagenesis, the mutant shows 8.43% of wild-type activity
-