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1.1.1.238: 12beta-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 12beta-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

3alpha,7alpha,12beta-trihydroxy-5beta-cholan-24-oate
+
NADP+
=
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate
 +
NADPH
 +
H+

Synonyms

12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.238 12beta-hydroxysteroid dehydrogenase

KM Value

KM Value on EC 1.1.1.238 - 12beta-hydroxysteroid dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0895
3,12-Dioxo-5beta-cholanoate
-
-
0.171
3,7,12-Trioxo-5beta-cholanoate
-
-
0.142
3,7,12-trioxotaureate
-
-
0.274
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoate
-
-
0.141
3alpha-Hydroxy-12-oxo-5beta-cholanoate
-
-
0.144
3alpha-Hydroxy-7,12-dioxo-5beta-cholanoate
-
-
0.0837
7,12-Dioxo-5beta-cholanoate
-
-
0.138
7alpha-Hydroxy-3,12-dioxo-5beta-cholanoate
-
-